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Nutanix on HPE Proliant Best Practices

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Nutanix on HPE ® ProLiant ® 1. Executive Summary | 4 1. Executive Summary Nutanix runs on HPE ® ProLiant ® rack-mount and integrated systems and general-purpose servers. Intended for datacenter administrators responsible for procuring, designing, installing, and operating Nutanix on HPE ProLiant, this best practice document can help steer the decision- making process when deploying Nutanix. This guide does not specifically provide guidance on technical issues solely related to HPE ProLiant systems. Nutanix and HPE announced their partnership in April 2019, to jointly launch HPE ® ProLiant ® DX integrated systems targeting datacenter and edge environments. Prior to this partnership, Nutanix also maintained a Hardware Compatibility List (HCL) of supported general-purpose HPE ® ProLiant ® DL Gen10 servers. For all new HPE deployments, we recommend HPE ProLiant DX integrated systems. Unless otherwise stated, the information in this document applies to both models. Organizations can procure Nutanix on HPE ProLiant DX in two ways: 1. A Nutanix-led traditional sales process, where the customer purchases an integrated system up front with a Nutanix software subscription. 2. By signing up for HPE GreenLake, an HPE-led usage-based model for consuming infrastructure, where the customer pays on a monthly basis. In either case, Nutanix and HPE collaborate behind the scenes to engineer, support, deploy, and offer advice for this joint solution. HPE ProLiant systems provide infrastructure that supports business objectives and growth. The Nutanix enterprise cloud software streamlines the datacenter by integrating server and storage resources into a turnkey system. When running Nutanix on HPE ProLiant, you no longer need a storage area network (SAN), which reduces the number of devices to purchase, deploy, and maintain and improves speed and agility. In this document, we address system life cycle operations that require special handling in the ProLiant environment, such as network cabling, firmware upgrades, and node replacement. Where multiple options are available, we provide the information you need to decide between them. We also highlight configurations and features that may be common in the field but that we don't recommend for Nutanix environments. The Nutanix Field Installation Guide for HPE ProLiant Servers offers step-by-step installation instructions; this guide supplements those instructions. We do not, however, intend to supplant or supersede any guidance, instructional manuals, or directives from HPE regarding ProLiant servers. Contact HPE directly for any issues that do not relate to Nutanix software systems.

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